|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
25-Hydroxyvitamin D3 1-alpha-Hydroxylase
|
|
Descriptor Spanish:
|
|
25-Hidroxivitamina D3 1-alfa-Hidroxilasa
|
|
Descriptor Portuguese:
|
|
25-Hidroxivitamina D3 1-alfa-Hidroxilase
|
|
Synonyms English:
|
|
25-Hydroxycholecalciferol-1-Hydroxylase
25-Hydroxyergocalciferol 1-alpha-Hydroxylase
25-Hydroxyvitamin D 1-alpha-Hydroxylase
25-Hydroxyvitamin D(3) 1 alpha-Hydroxylase
25-Hydroxyvitamin D2 1-hydroxylase
1-alpha-Hydroxylase, 25-Hydroxyergocalciferol
1-alpha-Hydroxylase, 25-Hydroxyvitamin D
1-hydroxylase, 25-Hydroxyvitamin D2
25 Hydroxycholecalciferol 1 Hydroxylase
25 Hydroxyergocalciferol 1 alpha Hydroxylase
25 Hydroxyvitamin D 1 alpha Hydroxylase
25 Hydroxyvitamin D2 1 hydroxylase
25 Hydroxyvitamin D3 1 alpha Hydroxylase
Calcidiol 1 Monooxygenase
Cytochrome P 450 CYP27B1
25-Hydroxycholecalciferol 1-Hydroxylase
CYP27B1
Calcidiol 1-Monooxygenase
Cytochrome P-450 CYP27B1
|
|
Tree Number:
|
|
D08.244.453.499.500
D08.244.453.915.400
D08.811.682.690.708.170.493.500
D08.811.682.690.708.170.915.400
D12.776.422.220.453.499.500
D12.776.422.220.453.915.400
|
|
Definition English:
|
|
A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP27B1 gene, converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol). |
|
History Note English:
|
|
2003 (1975); for 25-HYDROXYVITAMIN D2 1-HYDROXYLASE use STEROID HYDROXYLASES (NM) 1976-2002
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
7046
|
|
Unique Identifier:
|
|
D015090
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|